Eli Lilly has partnered with Swedish biotech Alzecure to develop ACD680, a preclinical small-molecule candidate aimed at modulating gamma-secretase, an enzyme linked to amyloid-beta production in Alzheimer’s disease. Following the announcement, Alzecure’s shares surged by 313%. ACD680 represents an innovative approach, targeting the early stages of amyloid production rather than addressing already formed plaques, as seen in other therapies like Lilly’s Kisunla. While Lilly’s Alzheimer’s pipeline now includes three amyloid-targeting assets, the company is also pursuing diverse strategies, including tau-targeting therapies, reflecting a growing complexity in Alzheimer’s research.
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Link to original article source: https://european-biotechnology.com/latest-news/alzecure-shares-soar-over-300-after-eli-lilly-strikes-alzheimers-deal-worth-over-1bn/

